Endocrine Abstracts

Epididymis is an androgen dependent organ with four main segments; initial segment (IS), caput, corpus and cauda. It is an essential site for post-testicular sperm maturation, as spermatozoa acquire fertilizing capacity during epididymal transit. Post-testicular maturation is dependent on the proteins expressed and secreted to the lumen by epididymal cells. Androgens regulate gene expression in epididymis in a segment-specific manner. Caput-specific genes are androgen regulate...